Glutaminase anticorps (C-Term)

N° du produit ABIN7464725

Cet anticorps anti-Glutaminase est un anticorps Lapin Polyclonal détectant Glutaminase dans WB, IF, IP, ICC et IHC (p). Adapté pour Humain.

Aperçu rapide pour Glutaminase anticorps (C-Term) (ABIN7464725)

Antigène: Glutaminase (GLS)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaminase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit anti-Glutaminase anticorps

Épitope: C-Term

Specificité: Specific for GAC but not KGA isoform

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human Glutaminase C (GAC). The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: MDA-MB-231

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Glutaminase

Antigène: Glutaminase (GLS)

Autre désignation: glutaminase

Sujet: Glutaminase , AAD20 , CASGID , EIEE71 , GAC , GAM , GLS1 , KGA,Sahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM]

Poids moléculaire: 65 kDa

ID gène: 2744

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, L'effet Warburg